Most of the programs don't consume too much of your computer's resources, however, there are some, such as Adobe Photoshop, which do. The first thing you need to do is to identify them and then close the demanding ones.
If you are a Windows user, you can easily identify them via the Task Manager (access it by pressing Ctrl + Shift + Esc) in the CPU column. If you use Windows 7 or below, click the Startup tab first. Close the programs which use more than 50% of your CPU
Check out the don't know how to close (quit) programs/applications solutions to learn how to close the programs.
Maybe a virus has infected your computer and occupied your CPU, i.e. uses 100% of it. Sometimes you can even identify it via the CPU column in the Task Manager (press Ctrl + Shift + Esc to access the Task Manager).
Usually, that process will have a random name, e.g. xyzasd.sd, and will use 100% of the CPU.
The next step will be to remove it. Check out the viruses/spywares/malware solutions to learn how to remove it.
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